Co-morbidity of Parkinson’s disease and Myasthenia gravis - a clinical case of bulgarian patient
Keywords:
co-morbidity, Parkinson’s disease, Myasthenia gravisAbstract
The simultaneous existence of Parkinson’s disease and Myasthenia gravis in the same person as a co-morbidity is very rare. Few cases are described in the world scientific literature. Whereas Parkinson’s disease is a neurodegenerative disease, Myasthenia gravis is with autoimmune genesis. We present a clinical case of a patient with idiopathic Parkinson’s disease with the onset 10 years ago, his first myasthenic complaints are since September 2012 with day-and-night fluctuations of the symptoms.
References
Milanov, I., Neurology, 2012, Medicine and Physical Education, Sofia, 1055
Ueno, S., Takahashi, M., Kajiyama. K. et al. (1987) Parkinson’s disease and myasthenia gravis: adverse effect of trihexyphenidyl on neuromuscular transmission. Neurology, 37: 832-833.
Ko-Pei Kao, Shang-Yeong Kwarf, Ko-Pin Lin at al, Coexistence of Parkinson’s disease and myasthenia gravis: a case report. Clinical Neurology and Neurosurgery, 95 (1993) 137-l 39
Iwasaki, Y., Wakata. N. and Kinoshita, M. (1988) Parkinsonism
induced by pyridostigmine. Acta Neurol. Stand., 78:236.
Fasano, A. Evoli, C. Piano,et al. Myasthenia gravis: An unrecognized cause of head drop in Parkinson’s disease. Parkinsonism and Related Disorders 14 (2008) 164–165.
Isin Unal-Cevik, Cagri Mesut Temucin Head drop in an elder Parkinson's disease after development of myasthenia gravis Movement Disorders (2009) Volume 24, Issue 13, 2024–2026
Levin,N.,Karussis, D., Abramsky,O. Parkinson’s disease associated with myasthenia gravis A report of 4 cases, J Neurol (2003) 250: 766–767
Dubois, B., Hauw, J.J., Ruberg, M., Serdaru, M., Javoy-Agid, F. and Agid, Y. (1985) Demence et maladie de Parkinson: correlations biochimiques et anatomo-cliniques. Rev.Neurol. (Paris), 141(3): 184-193.
Birtley. R.D.N., Rogerts, J.B., Thomas, B.H. Excretion and metabolism of (14C) pyridostigmine in the rat. Br. J. (1966) Pharmacol., 24: 393402.
Agid, Y., Javoy-Agid, F. and Ruberg, M. (1987) Biochemistry of neurotransmitters in Parkinson’s disease. In: Marsden, C.D. and Fahn, S. (Eds.), Movement Disorders, 2, Butterworths, London, pp. 166-230.
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Copyright (c) 2016 E. Chorbadjieva, D. Georgiev, I. Milanov
This work is licensed under a Creative Commons Attribution 4.0 International License.
