Risk assessment among patients with epilepsy and arterial hypertension

Abstract

Introduction: One of the most common somatic comorbid diseases of epilepsy is arterial hypertension. Cerebral complications are observed among not well compensated values of the arterial pressure and a long lasting disease. Each of these complications can lead to the emergence or deterioration of the already existing epilepsy.
Aim: The aim of the current research is a risk assessment among patients with epilepsy and comorbid arterial hypertension, considering some neurologic comorbidities as well as nature of epilepsy progress.
Contingent and methods: The research is clinical, epidemological, and retrospective for a period of ten years. Out of 1 624 patients with epilepsy diagnosis and one or more comorbid diseases, all 591 with epilepsy and arterial hypertension have been examined. The methods used include documentary analysis, clinical and laboratory examinations, and statistical methods.
Results: A statistically significant reliability (р<0,0001) has been observed in the presence of transient cerebral attacks (20,3%), cerebral stroke (15,2%) and cerebral haemorrhage (4,9%) among patients with arterial hypertension and epilepsy. There is statistically insignifical difference (р=0,810) comparing the higher frequency of epileptic seizures among patients with not well compensated (39,1%) compared to patients with well-compensated arterial hypertension (38,1%).
Conclusion: The comorbidity of arterial hypertension and epilepsy could lead to a deterioration of the patient's condition, taking into consideration different types of medications, the possibility of drug interactions, as well as the danger of some neurological complications.